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Anti-Peroxiredoxin 3 Polyclonal Antibody

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Catalog No. TMAB-10198

Anti-Peroxiredoxin 3 Polyclonal Antibody is a Rabbit antibody targeting Peroxiredoxin 3. Anti-Peroxiredoxin 3 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-Peroxiredoxin 3 Polyclonal Antibody

Anti-Peroxiredoxin 3 Polyclonal Antibody

😃Good
Catalog No. TMAB-10198
Anti-Peroxiredoxin 3 Polyclonal Antibody is a Rabbit antibody targeting Peroxiredoxin 3. Anti-Peroxiredoxin 3 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Peroxiredoxin 3 Polyclonal Antibody is a Rabbit antibody targeting Peroxiredoxin 3. Anti-Peroxiredoxin 3 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Dog,Horse,Rabbit)
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMitochondrion.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe Peroxiredoxin (Prdx, Prx, or Trx-Px) family of enzymes is a recently identified family of peroxidases found in free-living organisms. The six known isoforms (Prx1-6) play an important role in protecting lipids, enzymes and DNA against peroxides, such as hydrogen peroxide. The ubiquitously expressed peroxiredoxins have also been shown to play a role in apoptosis and cell differentiation. This is acomplished by the active cysteine of Prx reducing peroxides, which is then converted into a transient cysteine sulfenic acid or cysteine sulfinic acid. If Prx protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human PRDX3
Antigen Species
Human
Gene Name
PRDX3
Gene ID
Protein Name
Thioredoxin-dependent peroxide reductase, mitochondrial
Uniprot ID
Function
Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical-generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
Chemical Properties
Molecular WeightTheoretical: 21 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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