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Anti-Notch 2 Polyclonal Antibody
Catalog No. TMAB-09569 Copy Product Info
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Anti-Notch 2 Polyclonal Antibody is a Rabbit antibody targeting Notch 2. Anti-Notch 2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Notch 2 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-09569
Anti-Notch 2 Polyclonal Antibody is a Rabbit antibody targeting Notch 2. Anti-Notch 2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Notch 2 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Notch 2 Polyclonal Antibody is a Rabbit antibody targeting Notch 2. Anti-Notch 2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Pig,Rabbit) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Notch 2) Polyclonal Antibody, Unconjugated (TMAB-09569) at 1:400 overnight at 4°C, followed by a conjugated secondary antibody for 20 minutes and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Notch 2 intracellular domain: Nucleus. |
| Tissue Specificity | Expressed in the brain, heart, kidney, lung, skeletal muscle and liver. Ubiquitously expressed in the embryo. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. |
| Immunogen | KLH conjugated synthetic peptide: human Notch2 |
| Antigen Species | Human |
| Gene Name | NOTCH2 |
| Gene ID | |
| Protein Name | Neurogenic locus notch homolog protein 2 |
| Uniprot ID |
| Molecular Weight | Theoretical: 262 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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