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Anti-MACF1/ACF7 Polyclonal Antibody
😃Good
Catalog No. TMAB-08491
Anti-MACF1/ACF7 Polyclonal Antibody is a Rabbit antibody targeting MACF1/ACF7. Anti-MACF1/ACF7 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-MACF1/ACF7 Polyclonal Antibody
Anti-MACF1/ACF7 Polyclonal Antibody
😃Good
Catalog No. TMAB-08491
Anti-MACF1/ACF7 Polyclonal Antibody is a Rabbit antibody targeting MACF1/ACF7. Anti-MACF1/ACF7 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-MACF1/ACF7 Polyclonal Antibody is a Rabbit antibody targeting MACF1/ACF7. Anti-MACF1/ACF7 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Chicken,Cow,Sheep) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasmic, microtubule. Plasma membrane. Golgi apparatus. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Microtubule-actin crosslinking factor 1 (MACF1/ACF7) belongs to spectraplakin family of proteins which also includes mammalian Bpag1/dystonin, Drosophila Short Stop (Shot) and Caenorhabditis elegans Vab-10. These are large actin-microtubule linker molecules that are essential for various biological processes such as neuronal degeneration, wound healing, gastrulation. MACF1, located on mouse chromosome 4D2.2, was found to play an important role during neurogenesis- it was shown that MACF1 regulates the organization of neuronal microtubules which is essential for axon extension. Furthermore, MACF1 is required in controlling focal adhesion assembly and dynamics. MACF1 behaves as an actin-regulated ATPase and it has the ability to target microtubules that track along F-actin to focal adhesions. MACF1 was also implicated in regulating filopodia formation. |
| Immunogen | KLH conjugated synthetic peptide: human MACF1/ACF7 |
| Antigen Species | Human |
| Gene Name | Macf1 |
| Gene ID | |
| Protein Name | Microtubule-actin cross-linking factor 1 |
| Molecular Weight | Theoretical: 839 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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