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Anti-Synaptotagmin 5 Polyclonal Antibody
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Catalog No. TMAB-13322
Anti-Synaptotagmin 5 Polyclonal Antibody is a Rabbit antibody targeting Synaptotagmin 5. Anti-Synaptotagmin 5 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Synaptotagmin 5 Polyclonal Antibody
Anti-Synaptotagmin 5 Polyclonal Antibody
😃Good
Catalog No. TMAB-13322
Anti-Synaptotagmin 5 Polyclonal Antibody is a Rabbit antibody targeting Synaptotagmin 5. Anti-Synaptotagmin 5 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Synaptotagmin 5 Polyclonal Antibody is a Rabbit antibody targeting Synaptotagmin 5. Anti-Synaptotagmin 5 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein (By similarity). Recycling endosome membrane; Single-pass membrane protein (By similarity). Note=In mast cells, localizes to the endocytic recycling compartment (By similarity). |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 [PubMed 7597049]).[supplied by OMIM, Feb 2011]. |
| Immunogen | KLH conjugated synthetic peptide: human Synaptotagmin 5 |
| Antigen Species | Human |
| Gene Name | SYT5 |
| Gene ID | |
| Protein Name | Synaptotagmin-5 |
| Uniprot ID | |
| Function | May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface (By similarity). |
| Molecular Weight | Theoretical: 43 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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