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Anti-DZIP1 Polyclonal Antibody
😃Good
Catalog No. TMAB-05376
Anti-DZIP1 Polyclonal Antibody is a Rabbit antibody targeting DZIP1. Anti-DZIP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-DZIP1 Polyclonal Antibody
Anti-DZIP1 Polyclonal Antibody
😃Good
Catalog No. TMAB-05376
Anti-DZIP1 Polyclonal Antibody is a Rabbit antibody targeting DZIP1. Anti-DZIP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-DZIP1 Polyclonal Antibody is a Rabbit antibody targeting DZIP1. Anti-DZIP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Cytoplasm. Note: In testis, it is predominantly nuclear, with some cytoplasmic localization in spermatogonia. Co-localizes with DAZ and DAZL in primordial germ cells. |
| Tissue Specificity | Predominantly expressed in testis. Also expressed in fetal brain, adult oocytes and ovary. Expressed in undifferentiated ES cells. In testis, it is probably specifically expressed in germ cells. Expressed in mature germ cells and secondary spermatocytes, while it is weakly or not expressed in primary spermatocytes. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | DZIP1 (DAZ interacting protein 1) is also known as DZIP or DZIP2 and is a 867 amino acid protein which is expressed as three isoforms, designated DZIPb, DZIPt1 and DZIPt2. DZIP1 is localized to testis, oocytes, ovary and fetal brain, as well as in embryonic stem cells and germ cells. In testis, DZIP1 is localized to the nucleus and also shows some cytoplasmic distribution in spermatogonia. DZIP1 belongs to the C2H2-type zinc-finger protein family, and, characteristc of the C2H2-type zinc-finger protein family, DZIP1 contains one C2H2-type zinc-finger region through which it is thought to interact with DAZ, an interaction that promotes spermiogenesis. DZIP1 expression is not found in those afflicted with Sertoli cell-only syndrome (characterized by the absence of germ cells in the testis), suggesting that the lack of DZIP1 may be involved in the pathogenesis of Sertoli cell-only syndrome-induced male sterility. |
| Immunogen | KLH conjugated synthetic peptide: human DZIP1 |
| Antigen Species | Human |
| Gene Name | DZIP1 |
| Gene ID | |
| Protein Name | Zinc finger protein DZIP1 |
| Uniprot ID | |
| Function | DZIP1 may participate in spermatogenesis via its interaction with DAZ. Isoform 1 and isoform 2 interact with DAZ proteins. DZIP1 may also participate in a RNA-binding complex that functions in both ES cells and germ cells. There are three named isoforms. |
| Molecular Weight | Theoretical: 99 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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