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Anti-Synaptotagmin XII Polyclonal Antibody

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Catalog No. TMAB-13323

Anti-Synaptotagmin XII Polyclonal Antibody is a Rabbit antibody targeting Synaptotagmin XII. Anti-Synaptotagmin XII Polyclonal Antibody can be used in WB,FCM.

Anti-Synaptotagmin XII Polyclonal Antibody

Anti-Synaptotagmin XII Polyclonal Antibody

😃Good
Catalog No. TMAB-13323
Anti-Synaptotagmin XII Polyclonal Antibody is a Rabbit antibody targeting Synaptotagmin XII. Anti-Synaptotagmin XII Polyclonal Antibody can be used in WB,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Synaptotagmin XII Polyclonal Antibody is a Rabbit antibody targeting Synaptotagmin XII. Anti-Synaptotagmin XII Polyclonal Antibody can be used in WB,FCM.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Pig,Rabbit,Sheep)
Application
WB
FCM
Recommended Dose
WB: 1:500-2000; FCM: 2μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Synaptotagmin XII
Antigen Species
Human
Gene Name
SYT12
Gene ID
91683
Protein Name
Synaptotagmin-12
Uniprot ID
Q8IV01.1
Function
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.
Chemical Properties
Molecular WeightTheoretical: 47 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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