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Anti-A4GALT Polyclonal Antibody
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Catalog No. TMAB-02122
Alias UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase, UDP galactose beta D galactosyl beta1 R 4 alpha D galactosyltransferase, PK, P1/Pk synthase, P1, P(k) antigen synthase, P blood group(P one antigen), Lactosylceramide 4-alpha-galactosyltransferase, Lactosylceramide 4 alpha galactosyltransferase, Globotriaosylceramide synthase, Gb3S, GB3 synthase, CD77 synthase, alpha4Gal-T1, alpha4Gal T1, alpha-1, alpha 1 4 N acetylglucosaminyltransferase, alpha 1 4 galactosyltransferase, A4GAT_HUMAN, A4GALT1, A14GALT, 4-N-acetylglucosaminyltransferase, 4-galactosyltransferase, 4 N acetylglucosaminyltransferase
Anti-A4GALT Polyclonal Antibody is a Rabbit antibody targeting A4GALT. Anti-A4GALT Polyclonal Antibody can be used in WB.
Anti-A4GALT Polyclonal Antibody
Anti-A4GALT Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-02122Alias UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase, UDP galactose beta D galactosyl beta1 R 4 alpha D galactosyltransferase, PK, P1/Pk synthase, P1, P(k) antigen synthase, P blood group(P one antigen), Lactosylceramide 4-alpha-galactosyltransferase, Lactosylceramide 4 alpha galactosyltransferase, Globotriaosylceramide synthase, Gb3S, GB3 synthase, CD77 synthase, alpha4Gal-T1, alpha4Gal T1, alpha-1, alpha 1 4 N acetylglucosaminyltransferase, alpha 1 4 galactosyltransferase, A4GAT_HUMAN, A4GALT1, A14GALT, 4-N-acetylglucosaminyltransferase, 4-galactosyltransferase, 4 N acetylglucosaminyltransferase
Anti-A4GALT Polyclonal Antibody is a Rabbit antibody targeting A4GALT. Anti-A4GALT Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-A4GALT Polyclonal Antibody is a Rabbit antibody targeting A4GALT. Anti-A4GALT Polyclonal Antibody can be used in WB. |
| Synonyms | UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase, UDP galactose beta D galactosyl beta1 R 4 alpha D galactosyltransferase, PK, P1/Pk synthase, P1, P(k) antigen synthase, P blood group(P one antigen), Lactosylceramide 4-alpha-galactosyltransferase, Lactosylceramide 4 alpha galactosyltransferase, Globotriaosylceramide synthase, Gb3S, GB3 synthase, CD77 synthase, alpha4Gal-T1, alpha4Gal T1, alpha-1, alpha 1 4 N acetylglucosaminyltransferase, alpha 1 4 galactosyltransferase, A4GAT_HUMAN, A4GALT1, A14GALT, 4-N-acetylglucosaminyltransferase, 4-galactosyltransferase, 4 N acetylglucosaminyltransferase |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Dog,Cow,Sheep) |
| Verified Activity | Sample: Lane 1: Mouse Kidney tissue lysates Lane 2: Mouse Heart tissue lysates Lane 3: Mouse Testis tissue lysates Lane 4: Human HeLa cell lysates Primary: Anti-A4GALT (TMAB-02122) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kDa Observed band size: 50 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Golgi apparatus membrane; Single-pass type II membrane protein (Probable). |
| Tissue Specificity | Ubiquitous. Highly expressed in kidney, heart, spleen, liver, testis and placenta. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins.Expression of CD77, also called Gb3, sensitizes a cell to verotoxins, causing cellular injury that can lead to disease. Therefore, the complex regulation of CD77 biosynthesis and the activity of the enzymes involved, such as CD77 synthase, can be studied by compared gene expression between toxin-sensitive and insensitive tissues and cell lines. The highest tissue expression of CD77 synthase occurs in the kidney, mesenteric lymph node, spleen, and brain. Burkitt leukemia cells express very high levels of CD77 as well as CD77 synthase, and are sensitive to verotoxin induced apoptosis. These megakaryoblasts then never mature, leading to the arrest of platelet generation in the bone marrow, which may cause thrombocytopenia, a symptom associated with various hemorrhagic conditions. |
| Immunogen | KLH conjugated synthetic peptide: human A4GALT |
| Antigen Species | Human |
| Gene Name | A4GALT |
| Gene ID | |
| Protein Name | Lactosylceramide 4-alpha-galactosyltransferase |
| Uniprot ID | |
| Function | Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins. |
| Molecular Weight | Theoretical: 40 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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