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Anti-ProSAPiP1 Polyclonal Antibody

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Catalog No. TMAB-11793

Anti-ProSAPiP1 Polyclonal Antibody is a Rabbit antibody targeting ProSAPiP1. Anti-ProSAPiP1 Polyclonal Antibody can be used in WB,FCM.

Anti-ProSAPiP1 Polyclonal Antibody

Anti-ProSAPiP1 Polyclonal Antibody

😃Good
Catalog No. TMAB-11793
Anti-ProSAPiP1 Polyclonal Antibody is a Rabbit antibody targeting ProSAPiP1. Anti-ProSAPiP1 Polyclonal Antibody can be used in WB,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-ProSAPiP1 Polyclonal Antibody is a Rabbit antibody targeting ProSAPiP1. Anti-ProSAPiP1 Polyclonal Antibody can be used in WB,FCM.
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human,Dog,Pig,Cow,Horse,Rabbit)
Application
WB
FCM
Recommended Dose
WB: 1:500-2000; FCM: 1μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cytoplasm > cytoskeleton. Detected at synapses, postsynaptic density, synaptic spines and dendrites.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe ProSAP family of proteins contain many protein-protein interaction domains and serve as scaffolding mediators within the post-synaptic density (PSD) of excitatory brain synapses. The PSD is an electron-dense structure underneath the post-synaptic plasma membrane of excitatory synapses that anchors and clusters glutamate receptors opposite to the pre-synaptic neurotransmitter release site. Shank proteins contain PDZ modular domains that coordinate the synaptic localization of ion channels, receptors, signaling enzymes, and cell adhesion molecules. The PDZ domain mediates protein-protein interactions via the recognition of a conserved sequence motif at the C-terminus of their target protein(s). ProSAPiP1 (proline rich synapse associated protein interacting protein 1) is a 673 amino acid protein that interacts with the PDZ domain of Shank 3. ProSAPiP1 expression is brain-specific with highest expression within the cerebellum, hippocampus and cerebral cortex.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human ProSAPiP1
Antigen Species
Human
Gene Name
LZTS3
Gene ID
9762
Protein Name
Leucine zipper putative tumor suppressor 3
Uniprot ID
O60299
Chemical Properties
Molecular WeightTheoretical: 72 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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