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Anti-COUP-TF1 Polyclonal Antibody

Catalog No. TMAB-04594 Copy Product Info
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Anti-COUP-TF1 Polyclonal Antibody is a Rabbit antibody targeting COUP-TF1. Anti-COUP-TF1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-COUP-TF1 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-04594

Anti-COUP-TF1 Polyclonal Antibody is a Rabbit antibody targeting COUP-TF1. Anti-COUP-TF1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-COUP-TF1 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-COUP-TF1 Polyclonal Antibody is a Rabbit antibody targeting COUP-TF1. Anti-COUP-TF1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Pig,Cow,Sheep)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (rat lung tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (COUP-TF1) Polyclonal Antibody, Unconjugated (TMAB-04594) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
FormulationPreservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
Concentration1mg/ml
Research BackgroundCOUP transcription factors have been cloned in several species and identified as orphan members of the steroid/thyroid hormone receptor superfamily. COUP-TFI (also designated COUP or EAR-3) and ARP-1 (also designated COUP-TFII) exhibit highly regulated and overlapping expression in most tissues. COUP-TFs are highly expressed in the developing and central nervous system, suggesting that these factors may be important in neural development and differentiation. COUP-TFs can compete for binding to response elements which are common to other members of this family, including RAR, RXR, PPAR, HNF-4, VDR and TR. They have been shown to act as negative regulators as well as initiators of transcription.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human COUP-TF1
Antigen Species
Human
Gene Name
NR2F1
Gene ID
7025
Protein Name
COUP transcription factor 1
Uniprot ID
P10589
Function
Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiation of transcription. Binds to both direct repeats and palindromes of the 5'-AGGTCA-3' motif. Represses transcriptional activity of LHCG.
Chemical Properties
Molecular WeightTheoretical: 46 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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