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Anti-IL-1R1 Polyclonal Antibody 3

Catalog No. TMAB-07625 Copy Product Info
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Anti-IL-1R1 Polyclonal Antibody 3 is a Rabbit antibody targeting IL-1R1. Anti-IL-1R1 Polyclonal Antibody 3 can be used in WB.

Anti-IL-1R1 Polyclonal Antibody 3

Copy Product Info
🥰Excellent
Catalog No. TMAB-07625

Anti-IL-1R1 Polyclonal Antibody 3 is a Rabbit antibody targeting IL-1R1. Anti-IL-1R1 Polyclonal Antibody 3 can be used in WB.

Anti-IL-1R1 Polyclonal Antibody 3
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-IL-1R1 Polyclonal Antibody 3 is a Rabbit antibody targeting IL-1R1. Anti-IL-1R1 Polyclonal Antibody 3 can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Rat)
Verified Activity
Sample: Cerebrum (Mouse) Lysate at 40 μg
Primary: Anti-Acid IL-1R1 (TMAB-07625) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 63 kD
Observed band size: 65 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single-pass type I membrane protein. Cell membrane (Probable). Secreted.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II(IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. [provided by RefSeq].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: mouse IL-1R1
Antigen Species
Mouse
Gene Name
IL1R1
Gene ID
Protein Name
Interleukin-1 receptor type 1
Uniprot ID
Function
Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.
Chemical Properties
Molecular WeightTheoretical: 63 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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