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Anti-TMPRSS2 Polyclonal Antibody
😃Good
Catalog No. TMAB-13615
Anti-TMPRSS2 Polyclonal Antibody is a Rabbit antibody targeting TMPRSS2. Anti-TMPRSS2 Polyclonal Antibody can be used in WB,ELISA.
Anti-TMPRSS2 Polyclonal Antibody
Anti-TMPRSS2 Polyclonal Antibody
😃Good
Catalog No. TMAB-13615
Anti-TMPRSS2 Polyclonal Antibody is a Rabbit antibody targeting TMPRSS2. Anti-TMPRSS2 Polyclonal Antibody can be used in WB,ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-TMPRSS2 Polyclonal Antibody is a Rabbit antibody targeting TMPRSS2. Anti-TMPRSS2 Polyclonal Antibody can be used in WB,ELISA. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane and Secreted. Activated by cleavage and secreted. |
| Tissue Specificity | Expressed strongly in small intestine. Also expressed in prostate, colon, stomach and salivary gland. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors (1,2). The TMPRSS2 gene encodes a 492 amino acid multimeric serine protease, which is mainly expressed in the mouse prostate and kidney, and is also expressed in the human small intestine, prostate, colon, stomach and salivary gland (3,4). TMPRSS2 contains several domains, including a serine protease domain of the S1 family, a scavenger receptor cysteine-rich domain of group A, an LDL receptor class A domain and a transmembrane domain (3). TMPRSS2 is expressed as a full length form and a cleaved protease domain (5) and its expression is increased by androgenic hormones. TMPRSS2 is also expressed in prostate carcinoma, suggesting that it may play a role in prostate carcinogenesis (6). |
| Immunogen | Recombinant Protein: human TMPRSS2 protein |
| Antigen Species | Human |
| Gene Name | TMPRSS2 |
| Gene ID | |
| Protein Name | Transmembrane protease serine 2 |
| Uniprot ID | |
| Function | Expressed strongly in small intestine. Also expressed in prostate, colon, stomach and salivary gland. |
| Molecular Weight | Theoretical: 54 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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