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Anti-Nectin 4 Polyclonal Antibody
Catalog No. TMAB-09332 Copy Product Info
🥰Excellent
Anti-Nectin 4 Polyclonal Antibody is a Rabbit antibody targeting Nectin 4. Anti-Nectin 4 Polyclonal Antibody can be used in WB.
Anti-Nectin 4 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-09332
Anti-Nectin 4 Polyclonal Antibody is a Rabbit antibody targeting Nectin 4. Anti-Nectin 4 Polyclonal Antibody can be used in WB.
Anti-Nectin 4 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Nectin 4 Polyclonal Antibody is a Rabbit antibody targeting Nectin 4. Anti-Nectin 4 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Pig,Cow,Horse,Rabbit) |
| Verified Activity | 1. Sample: A431 (Human) Cell Lysate at 30 μg Thymus (Mouse) Lysate at 40 μg Primary: Anti-Nectin 4 (TMAB-09332) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kD Observed band size: 55 kD 2. Sample: MCF-7 (Human) Cell Lysate at 30 μg Primary: Anti-Nectin 4 (TMAB-09332) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kD Observed band size: 55 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein (Potential). Cell junction, adherens junction. Processed poliovirus receptor-related protein 4: Secreted. |
| Tissue Specificity | Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined. |
| Immunogen | KLH conjugated synthetic peptide: human Nectin 4 |
| Antigen Species | Human |
| Gene Name | NECTIN4 |
| Gene ID | |
| Protein Name | Nectin-4 |
| Uniprot ID | |
| Function | Self-associates. Interacts via its Ig-like V-type domain with PVRL1/nectin-1 Ig-like V-type domain. Interacts via its C-terminus with MLLT4. Binds to Measles virus protein H and acts as a receptor for this virus. |
| Molecular Weight | Theoretical: 53 kDa. Actual: 53 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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