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Anti-ABCB6 Polyclonal Antibody

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Catalog No. TMAB-02148
Alias UMAT, Ubiquitously-expressed mammalian ABC half transporter, Ubiquitously expressed mammalian ABC half transporter, PRP, P-glycoprotein-related protein, P glycoprotein related protein, MTABC3, Mt-ABC transporter 3, Mt ABC transporter 3, Mitochondrial precursor, Mitochondrial ABC transporter 3, Mitochondrial abc protein 3, mitochondrial, EST45597, ATP-binding cassette, sub-family B, member 6, mitochondrial precursor, ATP-binding cassette sub-family B member 6, ATP binding cassette, sub family B(MDR/TAP), member 6, ATP binding cassette sub family B member 6, mitochondrial precursor, ABCB6_HUMAN, ABCB-6, Abcb6, ABCB 6, ABC-14, ABC14, ABC transporter umat, ABC 14, ABC

Anti-ABCB6 Polyclonal Antibody is a Rabbit antibody targeting ABCB6. Anti-ABCB6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-ABCB6 Polyclonal Antibody

Anti-ABCB6 Polyclonal Antibody

Copy Product Info
😃Good
Catalog No. TMAB-02148Alias UMAT, Ubiquitously-expressed mammalian ABC half transporter, Ubiquitously expressed mammalian ABC half transporter, PRP, P-glycoprotein-related protein, P glycoprotein related protein, MTABC3, Mt-ABC transporter 3, Mt ABC transporter 3, Mitochondrial precursor, Mitochondrial ABC transporter 3, Mitochondrial abc protein 3, mitochondrial, EST45597, ATP-binding cassette, sub-family B, member 6, mitochondrial precursor, ATP-binding cassette sub-family B member 6, ATP binding cassette, sub family B(MDR/TAP), member 6, ATP binding cassette sub family B member 6, mitochondrial precursor, ABCB6_HUMAN, ABCB-6, Abcb6, ABCB 6, ABC-14, ABC14, ABC transporter umat, ABC 14, ABC
Anti-ABCB6 Polyclonal Antibody is a Rabbit antibody targeting ABCB6. Anti-ABCB6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-ABCB6 Polyclonal Antibody is a Rabbit antibody targeting ABCB6. Anti-ABCB6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
SynonymsUMAT, Ubiquitously-expressed mammalian ABC half transporter, Ubiquitously expressed mammalian ABC half transporter, PRP, P-glycoprotein-related protein, P glycoprotein related protein, MTABC3, Mt-ABC transporter 3, Mt ABC transporter 3, Mitochondrial precursor, Mitochondrial ABC transporter 3, Mitochondrial abc protein 3, mitochondrial, EST45597, ATP-binding cassette, sub-family B, member 6, mitochondrial precursor, ATP-binding cassette sub-family B member 6, ATP binding cassette, sub family B(MDR/TAP), member 6, ATP binding cassette sub family B member 6, mitochondrial precursor, ABCB6_HUMAN, ABCB-6, Abcb6, ABCB 6, ABC-14, ABC14, ABC transporter umat, ABC 14, ABC
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,GuineaPig)
Verified Activity
1. Tissue/cell: rat liver tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min;
Incubation: Anti-ABCB6 Polyclonal Antibody, Unconjugated (TMAB-02148) 1: 200, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining
2. Paraformaldehyde-fixed, paraffin embedded (rat liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (ABCB6) Polyclonal Antibody, Unconjugated (TMAB-02148) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded (rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (ABCB6) Polyclonal Antibody, Unconjugated (TMAB-02148) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane. Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum. Golgi apparatus.
Tissue SpecificityWidely expressed. High expression is detected in the retinal epithelium.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human ABCB6
Antigen Species
Human
Gene Name
ABCB6
Gene ID
Protein Name
ATP-binding cassette sub-family B member 6, mitochondrial
Uniprot ID
Function
Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis
Chemical Properties
Molecular WeightTheoretical: 94 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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