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Anti-ABCB6 Polyclonal Antibody (Synonyms: UMAT, Ubiquitously-expressed mammalian ABC half transporter, Ubiquit...)
Catalog No. TMAB-02148 Copy Product Info
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Anti-ABCB6 Polyclonal Antibody is a Rabbit antibody targeting ABCB6. Anti-ABCB6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-ABCB6 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-02148
Synonyms UMAT, Ubiquitously-expressed mammalian ABC half transporter, Ubiquitously expressed mammalian ABC half transporter, PRP, P-glycoprotein-related protein, P glycoprotein related protein, MTABC3, Mt-ABC transporter 3, Mt ABC transporter 3, Mitochondrial precursor, Mitochondrial ABC transporter 3, Mitochondrial abc protein 3, mitochondrial, EST45597, ATP-binding cassette, sub-family B, member 6, mitochondrial precursor, ATP-binding cassette sub-family B member 6, ATP binding cassette, sub family B(MDR/TAP), member 6, ATP binding cassette sub family B member 6, mitochondrial precursor, ABCB6_HUMAN, ABCB-6, Abcb6, ABCB 6, ABC-14, ABC14, ABC transporter umat, ABC 14, ABC
Anti-ABCB6 Polyclonal Antibody is a Rabbit antibody targeting ABCB6. Anti-ABCB6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-ABCB6 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-ABCB6 Polyclonal Antibody is a Rabbit antibody targeting ABCB6. Anti-ABCB6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Synonyms | UMAT, Ubiquitously-expressed mammalian ABC half transporter, Ubiquitously expressed mammalian ABC half transporter, PRP, P-glycoprotein-related protein, P glycoprotein related protein, MTABC3, Mt-ABC transporter 3, Mt ABC transporter 3, Mitochondrial precursor, Mitochondrial ABC transporter 3, Mitochondrial abc protein 3, mitochondrial, EST45597, ATP-binding cassette, sub-family B, member 6, mitochondrial precursor, ATP-binding cassette sub-family B member 6, ATP binding cassette, sub family B(MDR/TAP), member 6, ATP binding cassette sub family B member 6, mitochondrial precursor, ABCB6_HUMAN, ABCB-6, Abcb6, ABCB 6, ABC-14, ABC14, ABC transporter umat, ABC 14, ABC |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,GuineaPig) |
| Verified Activity | 1. Tissue/cell: rat liver tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min; Incubation: Anti-ABCB6 Polyclonal Antibody, Unconjugated (TMAB-02148) 1: 200, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining 2. Paraformaldehyde-fixed, paraffin embedded (rat liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (ABCB6) Polyclonal Antibody, Unconjugated (TMAB-02148) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. 3. Paraformaldehyde-fixed, paraffin embedded (rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (ABCB6) Polyclonal Antibody, Unconjugated (TMAB-02148) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum. Golgi apparatus. |
| Tissue Specificity | Widely expressed. High expression is detected in the retinal epithelium. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function. |
| Immunogen | KLH conjugated synthetic peptide: human ABCB6 |
| Antigen Species | Human |
| Gene Name | ABCB6 |
| Gene ID | |
| Protein Name | ATP-binding cassette sub-family B member 6, mitochondrial |
| Uniprot ID | |
| Function | Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis |
| Molecular Weight | Theoretical: 94 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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