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Antifungal agent 106
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Catalog No. T89311
Antifungalagent 106 (Compound Z31) is a benzoic acid derivative and a potential fungicide targeting Monilinia fructicola. It exhibits antifungal activity with an EC50 of 11.8 mg/L. The mechanism of action involves the disruption of cell membrane integrity, resulting in increased membrane permeability and the release of intracellular electrolytes, which impairs normal mycelial growth. Antifungalagent 106 is also applicable in research related to brown rot in stone fruits.
Antifungal agent 106
Antifungal agent 106
😃Good
Catalog No. T89311
Antifungalagent 106 (Compound Z31) is a benzoic acid derivative and a potential fungicide targeting Monilinia fructicola. It exhibits antifungal activity with an EC50 of 11.8 mg/L. The mechanism of action involves the disruption of cell membrane integrity, resulting in increased membrane permeability and the release of intracellular electrolytes, which impairs normal mycelial growth. Antifungalagent 106 is also applicable in research related to brown rot in stone fruits.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Antifungalagent 106 (Compound Z31) is a benzoic acid derivative and a potential fungicide targeting Monilinia fructicola. It exhibits antifungal activity with an EC50 of 11.8 mg/L. The mechanism of action involves the disruption of cell membrane integrity, resulting in increased membrane permeability and the release of intracellular electrolytes, which impairs normal mycelial growth. Antifungalagent 106 is also applicable in research related to brown rot in stone fruits. |
| Targets&IC50 | mTOR:0.8 μM |
| In vitro | Antifungal agent 106, at concentrations ranging from 3.125 to 50 mg/L, demonstrates inhibitory effects on M. fructicola by suppressing spore germination and mycelial formation. It induces cellular oxidative damage, enzyme inactivation, and cell membrane disruption in M. fructicola by prompting the overproduction of reactive oxygen species (ROS). |
| In vivo | When plants (pear) were treated with Antifungal agent 106 at concentrations of 100 mg/L and 200 mg/L and sprayed over a 24-hour period, they exhibited significantly lower incidence rates of brown rot and smaller lesion diameters, indicating that Antifungal agent 106 has inhibitory activity against brown rot in stone fruits. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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