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Anti-GPBP1 Polyclonal Antibody

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Catalog No. TMAB-06656

Anti-GPBP1 Polyclonal Antibody is a Rabbit antibody targeting GPBP1. Anti-GPBP1 Polyclonal Antibody can be used in WB.

Anti-GPBP1 Polyclonal Antibody

Anti-GPBP1 Polyclonal Antibody

😃Good
Catalog No. TMAB-06656
Anti-GPBP1 Polyclonal Antibody is a Rabbit antibody targeting GPBP1. Anti-GPBP1 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-GPBP1 Polyclonal Antibody is a Rabbit antibody targeting GPBP1. Anti-GPBP1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Sheep)
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Cytoplasm. According to PubMed:12842993, it localizes to the cytoplasm.
Tissue SpecificityWidely expressed. Some isoforms may be specifically expressed in veins and arteries (at protein level). Isoform 4 is widely expressed. Isoform 1, isoform 2 and isoform 3 may be specifically expressed in vascular smooth muscle cells.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundVascular wall-linked protein, or Vasculin, is primarily expressed in the arterial wall and in plasma. It is also differentially expressed in human atherogenesis. Alternative splicing of exon 3 of the Vasculin gene produces three variants. Vasculin binds to and activates the minimal self-sufficient promoter element (MSPE) of the mouse Ada gene promoter and binds to and partially suppresses the GC-rich promoter of the nonhomologous human TOP2A gene promoter. It acts as a nuclear factor that can form complexes with TATA-binding proteins, transcription factors TFIIB and TFIIF, RNA polymerase II and p300. The regulated expression of Vasculin in plaques suggests that it may be involved in atherogenesis, and its presence in plasma may implicate Vasculin as a marker for atherosclerosis.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human GPBP1/Vasculin
Antigen Species
Human
Gene Name
GPBP1
Gene ID
65056
Protein Name
Vasculin
Uniprot ID
Q86WP2
Function
Functions as a GC-rich promoter-specific transactivating transcription factor.
Chemical Properties
Molecular WeightTheoretical: 53 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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