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Anti-BTNL2 Polyclonal Antibody

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Catalog No. TMAB-03249

Anti-BTNL2 Polyclonal Antibody is a Rabbit antibody targeting BTNL2. Anti-BTNL2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-BTNL2 Polyclonal Antibody

Anti-BTNL2 Polyclonal Antibody

😃Good
Catalog No. TMAB-03249
Anti-BTNL2 Polyclonal Antibody is a Rabbit antibody targeting BTNL2. Anti-BTNL2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-BTNL2 Polyclonal Antibody is a Rabbit antibody targeting BTNL2. Anti-BTNL2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human,Dog,Cow,Horse,Sheep)
Application
WB
IHC-P
IHC-Fr
IF
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single-pass type II membrane.protein. Note=Isoform 2 is present in the nuclear, vesicle and.plasma membranes, isoform 3 is found in cytoplasmic vesicle.structures and is not membrane bound.
Tissue SpecificityExpressed in brain, heart, kidney, liver, pancreas, ovary, leukocyte, small intestine, testis and thymus..
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundButyrophilin is a glycoprotein that is specifically expressed on the apical surface of mammary epithelial cells during lactation and becomes incorporated as an integral protein into the membrane of the milk fat globule during the budding and secretion of fat droplets into milk. BTNL2 (butyrophilin-like protein 2), also known as BTL-II, is a 455 amino acid single-pass type II membrane protein that acts as a negative regulator of T cell proliferation. Expressed in thymus, brain, kidney, heart, liver, small intestine, testis, ovary, pancreas and leukocytes, BTNL2 exists as at least six alternatively spliced isoforms, which are encoded by a gene located on human chromosome 6. Expression of BTNL2 isoform 3 is associated with susceptibility to sarcoidosis type 2 (SS2), an immune disorder that causes chronic inflammatory granulomatous lesions.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human BTNL2
Antigen Species
Human
Gene Name
BTNL2
Gene ID
56244
Protein Name
Butyrophilin-like protein 2
Uniprot ID
Q9UIR0
Function
Negative regulator of T-cell proliferation.
Chemical Properties
Molecular WeightTheoretical: 50 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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