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Anti-LRIG2 Polyclonal Antibody

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Catalog No. TMAB-08390

Anti-LRIG2 Polyclonal Antibody is a Rabbit antibody targeting LRIG2. Anti-LRIG2 Polyclonal Antibody can be used in WB.

Anti-LRIG2 Polyclonal Antibody

Anti-LRIG2 Polyclonal Antibody

Copy Product Info
😃Good
Catalog No. TMAB-08390
Anti-LRIG2 Polyclonal Antibody is a Rabbit antibody targeting LRIG2. Anti-LRIG2 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-LRIG2 Polyclonal Antibody is a Rabbit antibody targeting LRIG2. Anti-LRIG2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Rat,Dog,Pig,Cow,Horse,Rabbit,GuineaPig)
Verified Activity
1. Sample: Lymph node (Mouse) Lysate at 40 μg
Primary: Anti-LRIG2 (TMAB-08390) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 117 kD
Observed band size: 117 kD
2. Sample: Thymus (Mouse) Lysate at 40 μg
Primary: Anti-LRIG2 (TMAB-08390) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 117 kD
Observed band size: 117 kD
3. Sample:
Lane 1: Human HeLa cell lysates
Lane 2: Human HepG2 cell lysates
Primary: Anti-LRIG2 (TMAB-08390) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 117 kDa
Observed band size: 117 kDa
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Single-pass type I membrane protein. Cytoplasm.
Tissue SpecificityDetected in all tissues analyzed.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundLRIG2 is produced in all human glioma cell lines and localizes to perinuclear compartments, cytoplasmic compartments and the cell surface. It acts as a negative feedback regulator of signaling through enhanced receptor ubiquitination and accelerated intracellular degradation. LRIG2 may function as a tumour suppressor since it downregulates the expression of EGF and the related proteins ErbB-2, ErbB-3 and ErbB-4, which all inhibit cancer cells from growth, migration and invasion.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human LRIG2
Antigen Species
Human
Gene Name
LRIG2
Gene ID
Protein Name
Leucine-rich repeats and immunoglobulin-like domains protein 2
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 117 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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