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Anti-HSD17B6 Polyclonal Antibody

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Catalog No. TMAB-07321

Anti-HSD17B6 Polyclonal Antibody is a Rabbit antibody targeting HSD17B6. Anti-HSD17B6 Polyclonal Antibody can be used in FCM.

Anti-HSD17B6 Polyclonal Antibody

Anti-HSD17B6 Polyclonal Antibody

😃Good
Catalog No. TMAB-07321
Anti-HSD17B6 Polyclonal Antibody is a Rabbit antibody targeting HSD17B6. Anti-HSD17B6 Polyclonal Antibody can be used in FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-HSD17B6 Polyclonal Antibody is a Rabbit antibody targeting HSD17B6. Anti-HSD17B6 Polyclonal Antibody can be used in FCM.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Pig,Horse)
Application
Recommended Dose
FCM: 1μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMicrosome membrane; Peripheral membrane protein; Lumenal side. Early endosome membrane; Peripheral membrane protein; Lumenal side (Potential).
Tissue SpecificityDetected in liver and prostate (at protein level). Detected in adult liver, lung, brain, placenta, prostate, adrenal gland, testis, mammary gland, spleen, spinal cord and uterus. Detected in caudate nucleus, and at lower levels in amygdala, corpus callosum, hippocampus, substantia nigra and thalamus. Detected in fetal lung, liver and brain.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. [provided by RefSeq, Aug 2013]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human HSD17B6
Antigen Species
Human
Gene Name
HSD17B6
Gene ID
Protein Name
17-beta-hydroxysteroid dehydrogenase type 6
Uniprot ID
Function
NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro). Has retinol dehydrogenase activity towards all-trans-retinol (in vitro). Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha-androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids.
Chemical Properties
Molecular WeightTheoretical: 33 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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