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Anti-NBL1 Polyclonal Antibody

Catalog No. TMAB-09259 Copy Product Info
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Anti-NBL1 Polyclonal Antibody is a Rabbit antibody targeting NBL1. Anti-NBL1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-NBL1 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-09259

Anti-NBL1 Polyclonal Antibody is a Rabbit antibody targeting NBL1. Anti-NBL1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-NBL1 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-NBL1 Polyclonal Antibody is a Rabbit antibody targeting NBL1. Anti-NBL1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (mouse ovary); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (NBL1) Polyclonal Antibody, Unconjugated (TMAB-09259) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted.
Tissue SpecificityMost abundant in normal lung and meningioma.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundNBL1 (Neuroblastoma, suppression of tumorigenicity 1) is a candidate tumor suppressor of neuroblastoma and may play a role in preventing cells from entering the final stage (G1/S) of the transformation process. NBL1 is a member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. It is a member of a class of glycoproteins shown to be secreted inhibitors of the transforming growth factor-beta (TGF-beta) and bone morphogenic protein pathways.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human NBL1/DAND1
Antigen Species
Human
Gene Name
NBL1
Gene ID
Protein Name
Neuroblastoma suppressor of tumorigenicity 1
Uniprot ID
Function
Possible candidate as a tumor suppressor gene of neuroblastoma. May play an important role in preventing cells from entering the final stage (G1/S) of the transformation process.
Chemical Properties
Molecular WeightTheoretical: 18 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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