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Anti-MAFG Polyclonal Antibody

Catalog No. TMAB-08507 Copy Product Info
🥰Excellent
Anti-MAFG Polyclonal Antibody is a Rabbit antibody targeting MAFG. Anti-MAFG Polyclonal Antibody can be used in WB.

Anti-MAFG Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-08507

Anti-MAFG Polyclonal Antibody is a Rabbit antibody targeting MAFG. Anti-MAFG Polyclonal Antibody can be used in WB.

Anti-MAFG Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-MAFG Polyclonal Antibody is a Rabbit antibody targeting MAFG. Anti-MAFG Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Sheep)
Verified Activity
Sample:
Hela (Human) Cell Lysate at 40 μg
JurkaT (Human) Cell Lysate at 40 μg
Primary: Anti-MAFG (TMAB-08507) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 18 kD
Observed band size: 18 kD
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
Tissue SpecificityHighly expressed in skeletal muscle. Also expressed in heart and brain.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundGlobin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 [PubMed 9166829]). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).[supplied by OMIM, Mar 2010]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human MAFG
Antigen Species
Human
Gene Name
MAFG
Gene ID
4097
Protein Name
Transcription factor MafG
Uniprot ID
O15525
Function
Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF-E2. Activates globin gene expression when associated with NF-E2. May be involved in signal transduction of extracellular H(+).
Chemical Properties
Molecular WeightTheoretical: 18 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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