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Anti-KIR3DL2 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting KIR3DL2. Anti-KIR3DL2 Monoclonal Antibody-Biotin can be used in ELISA,FCM,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μg | $142 | 12 days | 12 days | |
| 50 μg | $171 | 12 days | 12 days | |
| 100 μg | $239 | 12 days | 12 days |
| Description | Anti-KIR3DL2 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting KIR3DL2. Anti-KIR3DL2 Monoclonal Antibody-Biotin can be used in ELISA,FCM,IF. |
| Synonyms | p70 natural killer cell receptor clone CL-5, Natural killer-associated transcript 4, Killer cell immunoglobulin-like receptor 3DL2, CD158 antigen-like family member K |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of KIR3DL2 overexpressed 354F cells with TMAZ-0179B, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of KIR3DL2 protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in PBS. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Receptor on natural killer (NK) cells and T cells for MHC class I molecules (PubMed: 24018270, PubMed: 28636952). Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions (PubMed: 24018270). Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity (PubMed: 26928464) |
| Conjucates | Biotin |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | KIR3DL2 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Drug Target |
| Molecular Weight | 150 kDa |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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