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Anti-LY6E Polyclonal Antibody

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Catalog No. TMAB-08462

Anti-LY6E Polyclonal Antibody is a Rabbit antibody targeting LY6E. Anti-LY6E Polyclonal Antibody can be used in WB.

Anti-LY6E Polyclonal Antibody

Anti-LY6E Polyclonal Antibody

😃Good
Catalog No. TMAB-08462
Anti-LY6E Polyclonal Antibody is a Rabbit antibody targeting LY6E. Anti-LY6E Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-LY6E Polyclonal Antibody is a Rabbit antibody targeting LY6E. Anti-LY6E Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Rat)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Tissue SpecificityWidely expressed, predominantly in liver, kidney, ovary, spleen and peripheral blood Leukocytes.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
FormulationPreservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
Concentration1mg/ml
Research BackgroundThis gene belongs to the human Ly6 gene family and encodes a glycosylphosphatidyl-inositol (GPI)-anchored cell surface protein. The protein plays an important role in T cell physiology, oncogenesis and immunological regulation. The protein is also involved in modulation of viral infection by coronaviruses, SARS-CoV, MERS-CoV and SARS-CoV-2. [provided by RefSeq, Aug 2021]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: mouse LY6E
Antigen Species
Mouse
Gene Name
Ly6e
Gene ID
Protein Name
Lymphocyte antigen 6E
Uniprot ID
Function
GPI-anchored cell surface protein that regulates T-lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR) signaling by interacting with component CD3Z/CD247 at the plasma membrane, leading to CD3Z/CD247 phosphorylation modulation (By similarity).
Restricts the entry of human coronaviruses, including SARS-CoV, MERS-CoV and SARS-CoV-2, by interfering with spike protein-mediated membrane fusion (PubMed:32641482).
Also plays an essential role in placenta formation by acting as the main receptor for syncytin-A (SynA). Therefore, participates in the normal fusion of syncytiotrophoblast layer I (SynT-I) and in the proper morphogenesis of both fetal and maternal vasculatures within the placenta. May also act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity (By similarity).
Chemical Properties
Molecular WeightTheoretical: 14 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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