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Anti-LY6E Polyclonal Antibody
Catalog No. TMAB-08462 Copy Product Info
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Anti-LY6E Polyclonal Antibody is a Rabbit antibody targeting LY6E. Anti-LY6E Polyclonal Antibody can be used in WB.
Anti-LY6E Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-08462
Anti-LY6E Polyclonal Antibody is a Rabbit antibody targeting LY6E. Anti-LY6E Polyclonal Antibody can be used in WB.
Anti-LY6E Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-LY6E Polyclonal Antibody is a Rabbit antibody targeting LY6E. Anti-LY6E Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Rat) |
| Verified Activity | Sample: Thymus (Mouse) Lysate at 40 μg Primary: Anti-LY6e (TMAB-08462) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 1 4 kD Observed band size: 1 4 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Tissue Specificity | Widely expressed, predominantly in liver, kidney, ovary, spleen and peripheral blood Leukocytes. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| Concentration | 1mg/ml |
| Research Background | This gene belongs to the human Ly6 gene family and encodes a glycosylphosphatidyl-inositol (GPI)-anchored cell surface protein. The protein plays an important role in T cell physiology, oncogenesis and immunological regulation. The protein is also involved in modulation of viral infection by coronaviruses, SARS-CoV, MERS-CoV and SARS-CoV-2. [provided by RefSeq, Aug 2021] |
| Immunogen | KLH conjugated synthetic peptide: mouse LY6E |
| Antigen Species | Mouse |
| Gene Name | Ly6e |
| Gene ID | |
| Protein Name | Lymphocyte antigen 6E |
| Uniprot ID | |
| Function | GPI-anchored cell surface protein that regulates T-lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR) signaling by interacting with component CD3Z/CD247 at the plasma membrane, leading to CD3Z/CD247 phosphorylation modulation (By similarity).
Restricts the entry of human coronaviruses, including SARS-CoV, MERS-CoV and SARS-CoV-2, by interfering with spike protein-mediated membrane fusion (PubMed:32641482). Also plays an essential role in placenta formation by acting as the main receptor for syncytin-A (SynA). Therefore, participates in the normal fusion of syncytiotrophoblast layer I (SynT-I) and in the proper morphogenesis of both fetal and maternal vasculatures within the placenta. May also act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity (By similarity). |
| Molecular Weight | Theoretical: 14 kDa. Actual: 14 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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