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Anti-NALP4 Polyclonal Antibody 3
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Catalog No. TMAB-09216
Anti-NALP4 Polyclonal Antibody 3 is a Rabbit antibody targeting NALP4. Anti-NALP4 Polyclonal Antibody 3 can be used in WB.
Anti-NALP4 Polyclonal Antibody 3
Anti-NALP4 Polyclonal Antibody 3
😃Good
Catalog No. TMAB-09216
Anti-NALP4 Polyclonal Antibody 3 is a Rabbit antibody targeting NALP4. Anti-NALP4 Polyclonal Antibody 3 can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-NALP4 Polyclonal Antibody 3 is a Rabbit antibody targeting NALP4. Anti-NALP4 Polyclonal Antibody 3 can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm and Cytosol |
| Tissue Specificity | Expressed in the ovaries (at protein level). |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). This gene product has a demonstrated role as a negative regulator of autophagy and type I interferon signaling pathways as a result of protein interactions with its NACHT domain. The PYD domain has also been shown to be important in the inhibition of NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells). [provided by RefSeq, Dec 2016] |
| Immunogen | KLH conjugated synthetic peptide: human NALP4 |
| Antigen Species | Human |
| Gene Name | NLRP4 |
| Gene ID | |
| Protein Name | NACHT, LRR and PYD domains-containing protein 4 |
| Uniprot ID | |
| Function | Required for cytoplasmic lattice formation, thereby modulates the distribution of organelles during oocyte maturation and zygote development Required for preimplantation development in female fertilityMay be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors (By similarity). |
| Molecular Weight | Theoretical: 113 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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