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Antibacterial agent 18

Name: Antibacterial agent 18
Brand: TargetMol
SKU: T36657
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T36657Cas No. 1239602-35-7

Antibacterial agent 18 is a multi-arm AIE molecule with antibacterial activity, inhibiting the growth of both gram-positive and gram-negative bacteria by disrupting glycosylation and transpeptidation processes, affecting bacterial cell wall synthesis, useful for studying bacterial infections.

Antibacterial agent 18

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Purity: 98.08%

Catalog No. T36657Cas No. 1239602-35-7

Pack Size	Price	USA Warehouse	Global Warehouse
500 mg	$48	-	In Stock
1 g	$73	-	In Stock
1 mL x 10 mM (in DMSO)	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.08%

Appearance:Solid

Color:Yellow

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Antibacterial agent 18 is a multi-arm AIE molecule with antibacterial activity, inhibiting the growth of both gram-positive and gram-negative bacteria by disrupting glycosylation and transpeptidation processes, affecting bacterial cell wall synthesis, useful for studying bacterial infections.
In vitro	Antibacterial agent 18 (0.004-4 μg/mL; 24 h) inhibits the growth of Gram-positive and Gram-negative bacteria, with MICs ranging from 0.008-1 μg/mL[1].

Chemical Properties

Molecular Weight	605.64
Formula	C₃₉H₂₇NO₆
Cas No.	1239602-35-7
Smiles	O=C(O)C1=CC=C(C=C1)C2=CC=C(C=C2)N(C3=CC=C(C=C3)C4=CC=C(C=C4)C(=O)O)C5=CC=C(C=C5)C6=CC=C(C=C6)C(=O)O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 16 mg/mL (26.42 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6511 mL	8.2557 mL	16.5115 mL	82.5573 mL
5 mM	0.3302 mL	1.6511 mL	3.3023 mL	16.5115 mL
10 mM	0.1651 mL	0.8256 mL	1.6511 mL	8.2557 mL
20 mM	0.0826 mL	0.4128 mL	0.8256 mL	4.1279 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc