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Anti-XRCC1 Polyclonal Antibody

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Catalog No. TMAB-14217

Anti-XRCC1 Polyclonal Antibody is a Rabbit antibody targeting XRCC1. Anti-XRCC1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-XRCC1 Polyclonal Antibody

Anti-XRCC1 Polyclonal Antibody

😃Good
Catalog No. TMAB-14217
Anti-XRCC1 Polyclonal Antibody is a Rabbit antibody targeting XRCC1. Anti-XRCC1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-XRCC1 Polyclonal Antibody is a Rabbit antibody targeting XRCC1. Anti-XRCC1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat)
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Note=Accumulates at sites of DNA damage.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundXRCC1 is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. In testis XRCC1 is expressed at high levels.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human XRCC1
Antigen Species
Human
Gene Name
XRCC1
Gene ID
Protein Name
DNA repair protein XRCC1
Uniprot ID
Function
Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents.
Chemical Properties
Molecular WeightTheoretical: 69 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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