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Anti-VPS29 Polyclonal Antibody

Catalog No. TMAB-14136 Copy Product Info
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Anti-VPS29 Polyclonal Antibody is a Rabbit antibody targeting VPS29. Anti-VPS29 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-VPS29 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-14136

Anti-VPS29 Polyclonal Antibody is a Rabbit antibody targeting VPS29. Anti-VPS29 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-VPS29 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-VPS29 Polyclonal Antibody is a Rabbit antibody targeting VPS29. Anti-VPS29 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (VPS29) Polyclonal Antibody, Unconjugated (TMAB-14136) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Membrane. Endosome membrane.
Tissue SpecificityUbiquitous. Highly expressed in heart, lung, placenta, spleen, peripheral blood leukocytes, thymus, colon skeletal muscle, kidney and brain.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene belongs to a group of vacuolar protein sorting (VPS) genes that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. The protein encoded by this gene is a component of a large multimeric complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the trans-Golgi network. This VPS protein may be involved in the formation of the inner shell of the retromer coat for retrograde vesicles leaving the prevacuolar compartment. Alternative splice variants encoding different isoforms and representing non-protein coding transcripts have been found for this gene. [provided by RefSeq, Aug 2013]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human VPS29
Antigen Species
Human
Gene Name
VPS29
Gene ID
Protein Name
Vacuolar protein sorting-associated protein 29
Uniprot ID
Function
Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro).
Chemical Properties
Molecular WeightTheoretical: 21 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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