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Anti-ABCE1 Polyclonal Antibody (Synonyms: RNS4I, RNS 4I, RNASELI, RNASEL1, RNase L Inhibitor, RLI, Ribonuc...)
Catalog No. TMAB-02156 Copy Product Info
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Anti-ABCE1 Polyclonal Antibody is a Rabbit antibody targeting ABCE1. Anti-ABCE1 Polyclonal Antibody can be used in WB.
Anti-ABCE1 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-02156
Synonyms RNS4I, RNS 4I, RNASELI, RNASEL1, RNase L Inhibitor, RLI, Ribonuclease L(2'5' oligoisoadenylate synthetase dependent) inhibitor, Ribonuclease L(2' 5' oligoisoadenylate synthetase dependent) inhibitor, Ribonuclease L inhibitor, Ribonuclease 4 Inhibitor, OABP, HuHP68, HuHP 68, ATP-binding cassette sub-family E member 1, ATP binding cassette sub family E(OABP) member 1, ATP binding cassette sub family E member 1, ABCE1_HUMAN, ABCE1, ABCE 1, ABC38, ABC 38, 2''-5''-oligoadenylate-binding protein, 2'5' oligoadenylate binding protein, 2' 5' oligoadenylate binding protein
Anti-ABCE1 Polyclonal Antibody is a Rabbit antibody targeting ABCE1. Anti-ABCE1 Polyclonal Antibody can be used in WB.
Anti-ABCE1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-ABCE1 Polyclonal Antibody is a Rabbit antibody targeting ABCE1. Anti-ABCE1 Polyclonal Antibody can be used in WB. |
| Synonyms | RNS4I, RNS 4I, RNASELI, RNASEL1, RNase L Inhibitor, RLI, Ribonuclease L(2'5' oligoisoadenylate synthetase dependent) inhibitor, Ribonuclease L(2' 5' oligoisoadenylate synthetase dependent) inhibitor, Ribonuclease L inhibitor, Ribonuclease 4 Inhibitor, OABP, HuHP68, HuHP 68, ATP-binding cassette sub-family E member 1, ATP binding cassette sub family E(OABP) member 1, ATP binding cassette sub family E member 1, ABCE1_HUMAN, ABCE1, ABCE 1, ABC38, ABC 38, 2''-5''-oligoadenylate-binding protein, 2'5' oligoadenylate binding protein, 2' 5' oligoadenylate binding protein |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Chicken,Cow,Horse) |
| Verified Activity | Sample: Brain (Rat) Lysate at 40 μg Liver (Rat) Lysate at 40 μg Primary: Anti-ABCE1 (TMAB-02156) at 1/300 dilution Secondary: HRP conjugated Goat-Anti-rabbit IgG at 1/5000 dilution Predicted band size: 67 kD Observed band size: 66 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Mitochondrion. Note=Localized to clusters of virus formation at the plasma membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | ABCE1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. It is alternatively referred to as the RNase L inhibitor as it functions to block the activity of ribonuclease L(referenced from entrez gene). |
| Immunogen | KLH conjugated synthetic peptide: human ABCE1 |
| Antigen Species | Human |
| Gene Name | ABCE1 |
| Gene ID | |
| Protein Name | ATP-binding cassette sub-family E member 1 |
| Uniprot ID | |
| Function | Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly. |
| Molecular Weight | Theoretical: 67 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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