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Anti-PLCD1/NDNC3 Polyclonal Antibody

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Catalog No. TMAB-11531

Anti-PLCD1/NDNC3 Polyclonal Antibody is a Rabbit antibody targeting PLCD1/NDNC3. Anti-PLCD1/NDNC3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-PLCD1/NDNC3 Polyclonal Antibody

Anti-PLCD1/NDNC3 Polyclonal Antibody

Copy Product Info
😃Good
Catalog No. TMAB-11531
Anti-PLCD1/NDNC3 Polyclonal Antibody is a Rabbit antibody targeting PLCD1/NDNC3. Anti-PLCD1/NDNC3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-PLCD1/NDNC3 Polyclonal Antibody is a Rabbit antibody targeting PLCD1/NDNC3. Anti-PLCD1/NDNC3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human,Pig,Cow,Horse,Rabbit,Sheep,GuineaPig)
Verified Activity
1. Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (PLCD1/NDNC3) Polyclonal Antibody, Unconjugated (TMAB-11531) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
2. Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (PLCD1/NDNC3) Polyclonal Antibody, Unconjugated (TMAB-11531) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human PLCD1/NDNC3
Antigen Species
Human
Gene Name
PLCD1
Gene ID
Protein Name
1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase delta-1
Uniprot ID
Function
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. Essential for trophoblast and placental development.
Chemical Properties
Molecular WeightTheoretical: 86 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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