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Anti-Phospho-Cdc6 (Ser54) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cdc6 (Ser54). Anti-Phospho-Cdc6 (Ser54) Polyclonal Antibody can be used in ICC/IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
| Description | Anti-Phospho-Cdc6 (Ser54) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cdc6 (Ser54). Anti-Phospho-Cdc6 (Ser54) Polyclonal Antibody can be used in ICC/IF. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Dog,Pig,Horse,Rabbit,Sheep) |
| Application | |
| Recommended Dose | ICC/IF: 1:50-200 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Cytoplasm. The protein is nuclear in G1 and cytoplasmic in S-phase cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Cell cycle events are regulated by the sequential activation and deactivation of cyclin depended kinase (Cdks) and by the proteolysis of cyclins. The cell division cycle (Cdc) genes are required at various points in the cell cycle. Cdc6 is the human homolog of Saccharomyces cerevisiae Cdc6, which is involved in the initiation of DNA replication. Cdc6 is essential for assembling the pre-replicative complex that forms at origins of DNA replication in the G1 phase of the cell cycle in budding yeast (S. cerevisiae). Cdc6 is also involved in checkpoint controls that ensure that DNA replication is completed before initiation of mitosis. |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human Cdc6 around the phosphorylation site of Ser54 |
| Antigen Species | Human |
| Gene Name | CDC6 |
| Gene ID | |
| Protein Name | Cell division control protein 6 homolog |
| Uniprot ID | |
| Function | Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. |
| Molecular Weight | Theoretical: 63 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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