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Anti-CATSPER2 Polyclonal Antibody
Catalog No. TMAB-03697 Copy Product Info
🥰Excellent
Anti-CATSPER2 Polyclonal Antibody is a Rabbit antibody targeting CATSPER2. Anti-CATSPER2 Polyclonal Antibody can be used in WB.
Anti-CATSPER2 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-03697
Anti-CATSPER2 Polyclonal Antibody is a Rabbit antibody targeting CATSPER2. Anti-CATSPER2 Polyclonal Antibody can be used in WB.
Anti-CATSPER2 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CATSPER2 Polyclonal Antibody is a Rabbit antibody targeting CATSPER2. Anti-CATSPER2 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Sheep) |
| Verified Activity | 1. Sample: Hela (human) Cell Lysate at 40 μg 293T (human) Cell Lysate at 40 μg Primary: Anti-CATSPER2 (TMAB-03697) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD 2. Sample: testis (Mouse) Lysate at 40 μg Primary: Anti-CATSPER2 at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD 3. Sample: Testis (Rat) Lysate at 40 μg Primary: Anti-CATSPER2 (TMAB-03697) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell projection, cilium, flagellum membrane; Multi-pass membrane protein. Note=Specifically located in the principal piece of sperm tail. |
| Tissue Specificity | Testis-specific. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Calcium ions play a primary role in the regulation of sperm motility. This gene belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum. The protein family features a single repeat with six membrane-spanning segments and a predicted calcium-selective pore region. This gene is part of a tandem repeat on chromosome 15q15; the second copy of this gene is thought to be a pseudogene. Additional splice variants have been described but their full-length nature has not been determined. [provided by RefSeq, Aug 2008]. |
| Immunogen | KLH conjugated synthetic peptide: human CATSPER2 |
| Antigen Species | Human |
| Gene Name | CATSPER2 |
| Gene ID | |
| Protein Name | Cation channel sperm-associated protein 2 |
| Uniprot ID | |
| Function | Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials; it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH. |
| Molecular Weight | Theoretical: 58 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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