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Anti-PAFAH1B2 Polyclonal Antibody is a Rabbit antibody targeting PAFAH1B2. Anti-PAFAH1B2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
| Description | Anti-PAFAH1B2 Polyclonal Antibody is a Rabbit antibody targeting PAFAH1B2. Anti-PAFAH1B2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Horse,Sheep) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. |
| Tissue Specificity | Ubiquitous. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | PAFAH1B2, also known as PAFAHB, is a 229 amino acid cytoplasmic protein that belongs to the GDSL lipolytic enzyme family and the platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily. A ubiquitously expressed catalytic subunit of the cytosolic PAFAH1B heterotrimeric complex, PAFAH1B2 inactivates PAF by removing the acetyl group at the sn-2 position. Along with the beta subunit, PAFAH1B is made up of alpha and gamma subunits. The gene that encodes PAFAH1B2 consists of approximately 32,628 bases and maps to human chromosome 11q23.3. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that map to chromosome 11. |
| Immunogen | KLH conjugated synthetic peptide: human PAFAH1B2 |
| Antigen Species | Human |
| Gene Name | PAFAH1B2 |
| Gene ID | |
| Protein Name | Platelet-activating factor acetylhydrolase IB subunit alpha2 |
| Uniprot ID | |
| Function | Inactivates PAF by removing the acetyl group at the sn-2position. This is a catalytic subunit. |
| Molecular Weight | Theoretical: 25 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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