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Anti-ABC2 Polyclonal Antibody
😃Good
Catalog No. TMAB-02139
Anti-ABC2 Polyclonal Antibody is a Rabbit antibody targeting ABC2. Anti-ABC2 Polyclonal Antibody can be used in WB.
Anti-ABC2 Polyclonal Antibody
Anti-ABC2 Polyclonal Antibody
😃Good
Catalog No. TMAB-02139
Anti-ABC2 Polyclonal Antibody is a Rabbit antibody targeting ABC2. Anti-ABC2 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-ABC2 Polyclonal Antibody is a Rabbit antibody targeting ABC2. Anti-ABC2 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Phosphorylated by SMG1 |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | C17orf71 belongs to the UPF0487 family. There are 3 isoforms produced by alternative splicing.Positive control;Human Anaplastic Thyroid Carcinoma, Human Breast Carcinoma. |
| Immunogen | KLH conjugated synthetic peptide: human ABC2/C17orf71 |
| Antigen Species | Human |
| Gene Name | SMG8 |
| Gene ID | |
| Protein Name | Protein SMG8 |
| Uniprot ID | |
| Function | Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity. |
| Molecular Weight | Theoretical: 110 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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