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Anti-GCLM Polyclonal Antibody
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Catalog No. TMAB-06387
Anti-GCLM Polyclonal Antibody is a Rabbit antibody targeting GCLM. Anti-GCLM Polyclonal Antibody can be used in WB.
Anti-GCLM Polyclonal Antibody
Anti-GCLM Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-06387
Anti-GCLM Polyclonal Antibody is a Rabbit antibody targeting GCLM. Anti-GCLM Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-GCLM Polyclonal Antibody is a Rabbit antibody targeting GCLM. Anti-GCLM Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| Verified Activity | 1. Sample: Hela (Human) Cell Lysate at 30 μg A673 (Human) Cell Lysate at 30 μg Primary: Anti-GCLM (TMAB-06387) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kD Observed band size: 31 kD 2. Sample: NIH/3T3 (Mouse) Cell Lysate at 30 μg Primary: Anti-GCLM (TMAB-06387) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kD Observed band size: 31 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytosol |
| Tissue Specificity | In all tissues examined. Highest levels in skeletal muscle. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015] |
| Immunogen | KLH conjugated synthetic peptide: human GCLM |
| Antigen Species | Human |
| Gene Name | GCLM |
| Gene ID | |
| Protein Name | Glutamate--cysteine ligase regulatory subunit |
| Uniprot ID | |
| Function | This protein is involved in step 1 of the subpathway that synthesizes glutathione from L-cysteine and L-glutamate. |
| Molecular Weight | Theoretical: 31 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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