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Anti-Syntaxin 1A (brain) Polyclonal Antibody

Catalog No. TMAB-13336 Copy Product Info
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Anti-Syntaxin 1A (brain) Polyclonal Antibody is a Rabbit antibody targeting Syntaxin 1A (brain). Anti-Syntaxin 1A (brain) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Syntaxin 1A (brain) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-13336

Anti-Syntaxin 1A (brain) Polyclonal Antibody is a Rabbit antibody targeting Syntaxin 1A (brain). Anti-Syntaxin 1A (brain) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Syntaxin 1A
(brain) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Syntaxin 1A (brain) Polyclonal Antibody is a Rabbit antibody targeting Syntaxin 1A (brain). Anti-Syntaxin 1A (brain) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
Verified Activity
Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min;
Incubation: Anti-Syntaxin 1A (brain) Polyclonal Antibody, Unconjugated (TMAB-13336) 1: 600, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome. Isoform 2: Secreted (Probable).
Tissue SpecificityIsoform 1 is highly expressed in embryonic spinal chord and ganglia and in adult cerebellum and cerebral cortex. Isoform 2 is expressed in heart, liver, fat, skeletal muscle, kidney and brain.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundSyntaxin 1a is potentially involved in docking of synaptic vesicles at presynaptic active zones and may play a critical role in neurotransmitter exocytosis. Haploinsufficiency of STX1A may be the cause of certain cardiovascular and musculo skeletal abnormalities observed in Williams-Beuren syndrome (WBS), a rare developmental disorder.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Syntaxin 1A
Antigen Species
Human
Gene Name
STX1A
Gene ID
Protein Name
Syntaxin-1A
Uniprot ID
Function
Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
Chemical Properties
Molecular WeightTheoretical: 33 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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