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Anti-Phospho-14-3-3 theta (Ser232) Polyclonal Antibody

Catalog No. TMAB-10280 Copy Product Info
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Anti-Phospho-14-3-3 theta (Ser232) Polyclonal Antibody is a Rabbit antibody targeting Phospho-14-3-3 theta (Ser232). Anti-Phospho-14-3-3 theta (Ser232) Polyclonal Antibody can be used in FCM.

Anti-Phospho-14-3-3 theta (Ser232) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-10280

Anti-Phospho-14-3-3 theta (Ser232) Polyclonal Antibody is a Rabbit antibody targeting Phospho-14-3-3 theta (Ser232). Anti-Phospho-14-3-3 theta (Ser232) Polyclonal Antibody can be used in FCM.

Anti-Phospho-14-3-3 theta
(Ser232) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-14-3-3 theta (Ser232) Polyclonal Antibody is a Rabbit antibody targeting Phospho-14-3-3 theta (Ser232). Anti-Phospho-14-3-3 theta (Ser232) Polyclonal Antibody can be used in FCM.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Pig,Cow,Horse,Sheep)
Verified Activity
Blank control (blue line): HL60 (fixed with 70% ethanol (overninght at 4℃) and then permeabilized with 0.1% P Dilution: 1 μg /10^6 cells;
Isotype Control Antibody (orange line): Rabbit IgG.
Secondary Antibody (white blue line): Goat anti-rabbit IgG-PE, Dilution: 1 μg /test.
Application
Recommended Dose
FCM: 1μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. In neurons, axonally transported to the nerve terminals.
Tissue SpecificityAbundantly expressed in brain, heart and pancreas, and at lower levels in kidney and placenta. Up-regulated in the lumbar spinal cord from patients with sporadic amyotrophic lateral sclerosis (ALS) compared with controls, with highest levels of expression in individuals with predominant lower motor neuron involvement.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthesised phosphopeptide: human 14-3-3 Tau around the phosphorylation site of Ser232
Antigen Species
Human
Gene Name
YWHAQ
Gene ID
Protein Name
14-3-3 protein theta
Uniprot ID
Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
Chemical Properties
Molecular WeightTheoretical: 28 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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