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Anti-Phospho-14-3-3 theta (Ser232) Polyclonal Antibody
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Catalog No. TMAB-10280
Anti-Phospho-14-3-3 theta (Ser232) Polyclonal Antibody is a Rabbit antibody targeting Phospho-14-3-3 theta (Ser232). Anti-Phospho-14-3-3 theta (Ser232) Polyclonal Antibody can be used in FCM.
Anti-Phospho-14-3-3 theta (Ser232) Polyclonal Antibody
Anti-Phospho-14-3-3 theta (Ser232) Polyclonal Antibody
😃Good
Catalog No. TMAB-10280
Anti-Phospho-14-3-3 theta (Ser232) Polyclonal Antibody is a Rabbit antibody targeting Phospho-14-3-3 theta (Ser232). Anti-Phospho-14-3-3 theta (Ser232) Polyclonal Antibody can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-14-3-3 theta (Ser232) Polyclonal Antibody is a Rabbit antibody targeting Phospho-14-3-3 theta (Ser232). Anti-Phospho-14-3-3 theta (Ser232) Polyclonal Antibody can be used in FCM. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Pig,Cow,Horse,Sheep) |
| Application | |
| Recommended Dose | FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. In neurons, axonally transported to the nerve terminals. |
| Tissue Specificity | Abundantly expressed in brain, heart and pancreas, and at lower levels in kidney and placenta. Up-regulated in the lumbar spinal cord from patients with sporadic amyotrophic lateral sclerosis (ALS) compared with controls, with highest levels of expression in individuals with predominant lower motor neuron involvement. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthesised phosphopeptide: human 14-3-3 Tau around the phosphorylation site of Ser232 |
| Antigen Species | Human |
| Gene Name | YWHAQ |
| Gene ID | |
| Protein Name | 14-3-3 protein theta |
| Uniprot ID | |
| Function | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1. |
| Molecular Weight | Theoretical: 28 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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