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Anti-Nmnat1 Polyclonal Antibody

Catalog No. TMAB-09537 Copy Product Info
🥰Excellent
Anti-Nmnat1 Polyclonal Antibody is a Rabbit antibody targeting Nmnat1. Anti-Nmnat1 Polyclonal Antibody can be used in WB.

Anti-Nmnat1 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-09537

Anti-Nmnat1 Polyclonal Antibody is a Rabbit antibody targeting Nmnat1. Anti-Nmnat1 Polyclonal Antibody can be used in WB.

Anti-Nmnat1 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Nmnat1 Polyclonal Antibody is a Rabbit antibody targeting Nmnat1. Anti-Nmnat1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Chicken,Dog,Cow,Rabbit,Sheep)
Verified Activity
1. Sample: Testis (Mouse) Lysate at 40 μg
Primary: Anti-Nmnat1 (TMAB-09537) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 32 kD
Observed band size: 32 kD
2. Sample: Kidney (Mouse) Lysate at 40 μg
Primary: Anti-Nmnat1 (TMAB-09537) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 32 kD
Observed band size: 32 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
Tissue SpecificityWidely expressed with highest levels in skeletal muscle, heart and kidney. Also expressed in the liver pancreas and placenta. Widely expressed throughout the brain.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundNicotinamide adenine dinucleotide (NMNAT) is an essential cofactor involved in fundamental processes in cell metabolism. NMNAT plays a key role in NAD(+) biosynthesis, catalysing the condensation of nicotinamide mononucleotide and ATP, and yielding NAD(+) and pyrophosphate. NMNAT appears to be a substrate of nuclear kinases and contains at least three potential phosphorylation sites. The interaction of NMNAT with nuclear proteins is likely to be modulated by phosphorylation. NMNAT is widely expressed with highest levels in skeletal muscle, heart, liver and kidney.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Nmnat1
Antigen Species
Human
Gene Name
NMNAT1
Gene ID
Protein Name
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1
Uniprot ID
Function
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, prefers NAD(+) and NAAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following mechanical or toxic insults.
Chemical Properties
Molecular WeightTheoretical: 32 kDa. Actual: 32 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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