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Anti-PDCD1LG2 Polyclonal Antibody
😃Good
Catalog No. TMAB-10097
Anti-PDCD1LG2 Polyclonal Antibody is a Rabbit antibody targeting PDCD1LG2. Anti-PDCD1LG2 Polyclonal Antibody can be used in ICC/IF,FCM.
Anti-PDCD1LG2 Polyclonal Antibody
Anti-PDCD1LG2 Polyclonal Antibody
😃Good
Catalog No. TMAB-10097
Anti-PDCD1LG2 Polyclonal Antibody is a Rabbit antibody targeting PDCD1LG2. Anti-PDCD1LG2 Polyclonal Antibody can be used in ICC/IF,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-PDCD1LG2 Polyclonal Antibody is a Rabbit antibody targeting PDCD1LG2. Anti-PDCD1LG2 Polyclonal Antibody can be used in ICC/IF,FCM. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Cow) |
| Application | |
| Recommended Dose | ICC/IF: 1:100-500; FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform 3: Secreted (Probable). Isoform 2: Endomembrane system; Single-pass type I membrane protein. Isoform 1: Cell membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | B7DC is a 33kDa member of the immunoglobulin receptor superfamily expressed on DC, liver and a small subset of macrophages as well as a few transformed cell lines. B7DC has been reported to be stimulatory on dendritic cells when cross linked and to inhibit T cell activation upon engaging the PD1 receptor. B7DC has also been reported to bind to an alternative receptor and to mediate T cell activation through non PD1 mediated interactions. |
| Immunogen | KLH conjugated synthetic peptide: human PDCD1LG2 |
| Antigen Species | Human |
| Gene Name | PDCD1LG2 |
| Gene ID | |
| Protein Name | Programmed cell death 1 ligand 2 |
| Uniprot ID | |
| Function | Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity). |
| Molecular Weight | Theoretical: 29 kDa. Actual: 42 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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