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Anti-Ribonuclease 3/ECP Polyclonal Antibody

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Catalog No. TMAB-12250

Anti-Ribonuclease 3/ECP Polyclonal Antibody is a Rabbit antibody targeting Ribonuclease 3/ECP. Anti-Ribonuclease 3/ECP Polyclonal Antibody can be used in WB,ICC/IF.

Anti-Ribonuclease 3/ECP Polyclonal Antibody

Anti-Ribonuclease 3/ECP Polyclonal Antibody

😃Good
Catalog No. TMAB-12250
Anti-Ribonuclease 3/ECP Polyclonal Antibody is a Rabbit antibody targeting Ribonuclease 3/ECP. Anti-Ribonuclease 3/ECP Polyclonal Antibody can be used in WB,ICC/IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Ribonuclease 3/ECP Polyclonal Antibody is a Rabbit antibody targeting Ribonuclease 3/ECP. Anti-Ribonuclease 3/ECP Polyclonal Antibody can be used in WB,ICC/IF.
Ig Type
IgG
Reactivity
Human
Application
WB
ICC/IF
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasmic granule. Matrix of eosinophil's large specific granule.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundECP is a 160 amino acid potent cytotoxic secretory protein that belongs to the pancreatic ribonuclease family. ECP localizes to the granule matrix of the eosinophil and is involved in the immune response system. ECP is a cytotoxin, neurotoxin and helminthotoxin that is secreted by activated human eosinophils. ECP exhibits anti-parasitic, antibacterial and ribonucleolytic activities. It has been suggested that ECP induces the neurotoxic effect known as the Gordon phenomenon, a syndrome manifested by ataxia, muscular rigidity, paralysis, and tremor that may lead to death. ECP is considered a marker of eosinophilic inflammation and high levels have been found in cases of active asthma and other allergic diseases
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Ribonuclease 3
Antigen Species
Human
Gene Name
RNASE3
Gene ID
6037
Protein Name
Eosinophil cationic protein
Uniprot ID
P12724
Function
Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity.
Chemical Properties
Molecular WeightTheoretical: 16 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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