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Anti-CYFIP2 Polyclonal Antibody

Catalog No. TMAB-04860 Copy Product Info
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Anti-CYFIP2 Polyclonal Antibody is a Rabbit antibody targeting CYFIP2. Anti-CYFIP2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-CYFIP2 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-04860

Anti-CYFIP2 Polyclonal Antibody is a Rabbit antibody targeting CYFIP2. Anti-CYFIP2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-CYFIP2 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CYFIP2 Polyclonal Antibody is a Rabbit antibody targeting CYFIP2. Anti-CYFIP2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Chicken,Pig,Cow,Horse,Sheep)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (CYFIP2) Polyclonal Antibody, Unconjugated (TMAB-04860) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Cytoplasm, perinuclear region. Cell junction , synapse, synaptosome. Note: Highly expressed in the perinuclear region. Enriched in synaptosomes. Treatment with leptomycin-B triggers translocation to the nucleus.
Tissue SpecificityExpressed in T-cells. Increased expression is observed in CD4+ T-lymphocytes from patients with multiple sclerosis (at protein level).
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundCYFIP2 is involved in T cell adhesion and p53 dependent induction of apoptosis. It does not bind RNA but is up regulated significantly in CD4+ T lymphocytes from patients with multiple sclerosis. There are 2 isoforms produced by alternative splicing.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CYFIP2
Antigen Species
Human
Gene Name
CYFIP2
Gene ID
Protein Name
Cytoplasmic FMR1-interacting protein 2
Uniprot ID
Function
Involved in T-cell adhesion and p53/TP53-dependent induction of apoptosis. Does not bind RNA
Chemical Properties
Molecular WeightTheoretical: 146 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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