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Anti-SERBP1 Polyclonal Antibody
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Catalog No. TMAB-12665
Anti-SERBP1 Polyclonal Antibody is a Rabbit antibody targeting SERBP1. Anti-SERBP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-SERBP1 Polyclonal Antibody
Anti-SERBP1 Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-12665
Anti-SERBP1 Polyclonal Antibody is a Rabbit antibody targeting SERBP1. Anti-SERBP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-SERBP1 Polyclonal Antibody is a Rabbit antibody targeting SERBP1. Anti-SERBP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Horse,Rabbit) |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded (Mouse kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (SERBP1) Polyclonal Antibody, Unconjugated (TMAB-12665) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded (Human brain glioma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (SERBP1) Polyclonal Antibody, Unconjugated (TMAB-12665) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. 3. Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (SERBP1) Polyclonal Antibody, Unconjugated (TMAB-12665) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus. Cytoplasm, perinuclear region. |
| Tissue Specificity | Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | SERBP1 (Plasminogen activator inhibitor 1 RNA-binding protein) may play a role in the regulation of mRNA stability. SERBP1 binds to the 3’-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. SERBP1 interacts with CHD3 and is localized in cytoplasmic and nuclear. It is expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain. |
| Immunogen | KLH conjugated synthetic peptide: human SERBP1 |
| Antigen Species | Human |
| Gene Name | SERBP1 |
| Gene ID | |
| Protein Name | Plasminogen activator inhibitor 1 RNA-binding protein |
| Uniprot ID | |
| Function | May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. |
| Molecular Weight | Theoretical: 45 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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