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Anti-ZNF281 Polyclonal Antibody

Catalog No. TMAB-14362 Copy Product Info
🥰Excellent
Anti-ZNF281 Polyclonal Antibody is a Rabbit antibody targeting ZNF281. Anti-ZNF281 Polyclonal Antibody can be used in WB.

Anti-ZNF281 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-14362

Anti-ZNF281 Polyclonal Antibody is a Rabbit antibody targeting ZNF281. Anti-ZNF281 Polyclonal Antibody can be used in WB.

Anti-ZNF281 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ZNF281 Polyclonal Antibody is a Rabbit antibody targeting ZNF281. Anti-ZNF281 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Chicken,Pig,Cow,Horse,Sheep)
Verified Activity
Sample: 293T (Human) Cell Lysate at 30 μg
Primary: Anti-ZNF281 (TMAB-14362) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 97 kD
Observed band size: 100 kD
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundZinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF281, also known as GC-box-binding zinc finger protein 1, ZBP-99 or ZNP-99 (zinc finger DNA-binding protein 99), is a zinc finger protein that belongs to the Krüppel C2H2-type zinc finger protein family. It is expressed ubiquitously at low levels with predominant expression in kidney, liver, lymphocytes and placenta. ZNF281 localizes to the nucleus and contains four C2H2-type zinc fingers. ZNF281 plays a role in repressing the transcription of a variety of genes including Gastrin and ODC (ornithine decarboxylase). In particular, ZNF281 functions by binding to the G-rich box in the enhancer region of the gene. Upon DNA damage, ZNF281 may become phosphorylated by Atm or ATR.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: Human ZNF281
Antigen Species
Human
Gene Name
ZNF281
Gene ID
23528
Protein Name
Zinc finger protein 281
Uniprot ID
Q9Y2X9
Function
Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin and ornithine decarboxylase. Binds to the G-rich box in the enhancer region of these genes.
Chemical Properties
Molecular WeightTheoretical: 97 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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