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Anti-C14orf174 Polyclonal Antibody

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Catalog No. TMAB-03303

Anti-C14orf174 Polyclonal Antibody is a Rabbit antibody targeting C14orf174. Anti-C14orf174 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-C14orf174 Polyclonal Antibody

Anti-C14orf174 Polyclonal Antibody

Copy Product Info
😃Good
Catalog No. TMAB-03303
Anti-C14orf174 Polyclonal Antibody is a Rabbit antibody targeting C14orf174. Anti-C14orf174 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-C14orf174 Polyclonal Antibody is a Rabbit antibody targeting C14orf174. Anti-C14orf174 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Dog,Cow,Rabbit,Sheep)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (C14orf174) Polyclonal Antibody, Unconjugated (TMAB-03303) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundC14orf174, is a 674 amino acid protein that contains one SAM (sterile alpha motif) domain. Existing as two alternatively spliced isoforms,C14orf174 is encoded by a gene that maps to human chromosome 14q24.3. Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein Bcl-3 in the (14;19) translocations found in a variety of B cell malignancies.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human SAMD15/C14orf174
Antigen Species
Human
Gene Name
SAMD15
Gene ID
Protein Name
Sterile alpha motif domain-containing protein 15
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 77 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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