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Anti-WASP Polyclonal Antibody
Catalog No. TMAB-14159 Copy Product Info
🥰Excellent
Anti-WASP Polyclonal Antibody is a Rabbit antibody targeting WASP. Anti-WASP Polyclonal Antibody can be used in WB.
Anti-WASP Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-14159
Anti-WASP Polyclonal Antibody is a Rabbit antibody targeting WASP. Anti-WASP Polyclonal Antibody can be used in WB.
Anti-WASP Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-WASP Polyclonal Antibody is a Rabbit antibody targeting WASP. Anti-WASP Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Cow,Rabbit) |
| Verified Activity | 1. Sample: Spleen (Mouse) Lysate at 40 μg Raji Cell (Human) Lysate at 30 μg Primary: Anti-WASP (TMAB-14159) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kD Observed band size: 50 kD 2. Sample: U937 (Human) Cell Lysate at 30 μg Primary: Anti-WASP (TMAB-14159) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kD Observed band size: 53 kD 3. Sample: JurkaT (Human) Cell Lysate at 30 μg Raji (Human) Cell Lysate at 30 μg Primary: Anti-WASP (TMAB-14159) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kD Observed band size: 53 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm; cytoskeleton. |
| Tissue Specificity | Expressed predominantly in the thymus. Also found, to a much lesser extent, in the spleen |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The Wiskott-Aldrich syndrome (WAS) is a disorder that results from a monogenic defect that has been mapped to the short arm of the X chromosome. WAS is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative disease. The gene that is mutated in the syndrome encodes a proline-rich protein of unknown function designated WAS protein (WASP). A clue to WASP function came from the observation that T cells from affected males had an irregular cellular morphology and a disarrayed cytoskeleton suggesting the involvement of WASP in cytoskeletal organization. Close examination of the WASP sequence revealed a putative Cdc42/Rac interacting domain, homologous with those found in PAK65 and ACK. Subsequent investigation has shown WASP to be a true downstream effector of Cdc42. |
| Immunogen | KLH conjugated synthetic peptide: human WASP |
| Antigen Species | Human |
| Gene Name | WAS |
| Gene ID | |
| Protein Name | Wiskott-Aldrich syndrome protein |
| Uniprot ID | |
| Function | Effector protein for Rho-type GTPases, providing a link with the Arp2/3 complex that regulates the structure and dynamics of the actin cytoskeleton. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. |
| Molecular Weight | Theoretical: 53 kDa. Actual: 50-53 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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