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Anti-KCNAB1/Kv beta 1 Polyclonal Antibody
😃Good
Catalog No. TMAB-07924
Anti-KCNAB1/Kv beta 1 Polyclonal Antibody is a Rabbit antibody targeting KCNAB1/Kv beta 1. Anti-KCNAB1/Kv beta 1 Polyclonal Antibody can be used in WB.
Anti-KCNAB1/Kv beta 1 Polyclonal Antibody
Anti-KCNAB1/Kv beta 1 Polyclonal Antibody
😃Good
Catalog No. TMAB-07924
Anti-KCNAB1/Kv beta 1 Polyclonal Antibody is a Rabbit antibody targeting KCNAB1/Kv beta 1. Anti-KCNAB1/Kv beta 1 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-KCNAB1/Kv beta 1 Polyclonal Antibody is a Rabbit antibody targeting KCNAB1/Kv beta 1. Anti-KCNAB1/Kv beta 1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Rabbit,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. |
| Tissue Specificity | In brain, expression is most prominent in caudate nucleus, hippocampus and thalamus. Significant expression also detected in amygdala and subthalamic nucleus. Also expressed in both healthy and cardiomyopathic heart. Up to four times more abundant in left ventricle than left atrium. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming å subunits (KV), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. KV∫, also known as KCNAB1 (potassium voltage-gated channel, shaker-related subfamily, beta member 1), is a 419 amino acid accessory K+ channel protein that exists as three alternatively spliced isoforms and regulates the activity of the pore-forming å subunit. It is expressed in brain, with highest levels detected in caudate nucleus, hippocampus and thalamus. |
| Immunogen | KLH conjugated synthetic peptide: human KCNAB1/Kv beta 1 |
| Antigen Species | Human |
| Gene Name | KCNAB1 |
| Gene ID | |
| Protein Name | Voltage-gated potassium channel subunit beta-1 |
| Uniprot ID | |
| Function | Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. All three isoforms alter the functional properties of Kv1.4 and Kv1.5. Isoform KvB1.2 has no effect on Kv1.1, Kv1.2 or Kv2.1. |
| Molecular Weight | Theoretical: 47 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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