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Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2
Catalog No. TMAB-10725 Copy Product Info
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Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-GAB2 (Ser159). Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2 can be used in WB.
Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2
Copy Product Info🥰Excellent
Catalog No. TMAB-10725
Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-GAB2 (Ser159). Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2 can be used in WB.
Anti-Phospho-GAB2
(Ser159) Polyclonal Antibody 2
(Ser159) Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-GAB2 (Ser159). Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2 can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Chicken,Pig,Horse,Rabbit) |
| Verified Activity | Sample: Embryo (Mouse) Lysate at 40 μg Primary: Anti-phospho-GAB2 (Ser159) (TMAB-10725) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 74 kD Observed band size: 72 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Cell membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009] |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human GAB2 around the phosphorylation site of Ser159 |
| Antigen Species | Human |
| Gene Name | GAB2 |
| Gene ID | |
| Protein Name | GRB2-associated-binding protein 2 |
| Uniprot ID | |
| Function | Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis. |
| Molecular Weight | Theoretical: 74 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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