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Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2
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Catalog No. TMAB-10725
Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-GAB2 (Ser159). Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2 can be used in WB.
Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2
Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2
😃Good
Catalog No. TMAB-10725
Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-GAB2 (Ser159). Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2 can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-GAB2 (Ser159). Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2 can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Chicken,Pig,Horse,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Cell membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009] |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human GAB2 around the phosphorylation site of Ser159 |
| Antigen Species | Human |
| Gene Name | GAB2 |
| Gene ID | |
| Protein Name | GRB2-associated-binding protein 2 |
| Uniprot ID | |
| Function | Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis. |
| Molecular Weight | Theoretical: 74 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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