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Anti-ATIC/PURH Polyclonal Antibody

Catalog No. TMAB-02932 Copy Product Info
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Anti-ATIC/PURH Polyclonal Antibody is a Rabbit antibody targeting ATIC/PURH. Anti-ATIC/PURH Polyclonal Antibody can be used in WB.

Anti-ATIC/PURH Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-02932

Anti-ATIC/PURH Polyclonal Antibody is a Rabbit antibody targeting ATIC/PURH. Anti-ATIC/PURH Polyclonal Antibody can be used in WB.

Anti-ATIC/PURH Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ATIC/PURH Polyclonal Antibody is a Rabbit antibody targeting ATIC/PURH. Anti-ATIC/PURH Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit)
Verified Activity
Sample:
K562 (Human) Cell Lysate at 30 μg
HepG2 (Human) Cell Lysate at 30 μg
Primary: Anti-ATIC’PURH (TMAB-02932) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 65 kD
Observed band size: 65 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities. AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyzes the second to last step in purine biosynthesis, playing an important role in the production of nucleotides and IMP. Defects in the ATIC transformylase gene can cause AICA-rebsuria, also designated AICA-ribosiduria, an inborn error in purine biosynthesis that is neurologically cataclysmic. Individuals with AICA-rebosuria accumulate AICA-riboside, also designated ZMP, and its derivatives in erythrocytes and fibroblasts. Patients also excrete very large amounts of AICA-riboside in the urine. Mental retardation, epilepsy, dysmorphic features and congenital blindness are all symptoms of this disease.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human ATIC/AICAR transformylase
Antigen Species
Human
Gene Name
ATIC
Gene ID
Protein Name
Bifunctional purine biosynthesis protein ATIC
Uniprot ID
Function
Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis.
Chemical Properties
Molecular WeightTheoretical: 65 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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