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Anti-GADL1 Polyclonal Antibody

Catalog No. TMAB-06271 Copy Product Info
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Anti-GADL1 Polyclonal Antibody is a Rabbit antibody targeting GADL1. Anti-GADL1 Polyclonal Antibody can be used in WB.

Anti-GADL1 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-06271

Anti-GADL1 Polyclonal Antibody is a Rabbit antibody targeting GADL1. Anti-GADL1 Polyclonal Antibody can be used in WB.

Anti-GADL1 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-GADL1 Polyclonal Antibody is a Rabbit antibody targeting GADL1. Anti-GADL1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human,Bee)
Verified Activity
Sample:
Lane 1: Mouse Cerebellum tissue lysates
Lane 2: Mouse Cerebrum tissue lysates
Lane 3: Mouse Muscle tissue lysates
Lane 4: Rat Cerebrum tissue lysates
Lane 5: Rat Muscle tissue lysates
Primary: Anti-GADL1 (TMAB-06271) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 59 kDa
Observed band size: 60, 50 kDa
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThere are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 transiently activates to assist in GABA production. As a member of the group II decarboxylase family, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity. There are two isoforms of GADL1 that exist as a result of alternative splicing events.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human GADL1
Antigen Species
Human
Gene Name
GADL1
Gene ID
Protein Name
Acidic amino acid decarboxylase GADL1
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 59 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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