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Anti-KMT2D/ALL1 Polyclonal Antibody
😃Good
Catalog No. TMAB-08138
Anti-KMT2D/ALL1 Polyclonal Antibody is a Rabbit antibody targeting KMT2D/ALL1. Anti-KMT2D/ALL1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-KMT2D/ALL1 Polyclonal Antibody
Anti-KMT2D/ALL1 Polyclonal Antibody
😃Good
Catalog No. TMAB-08138
Anti-KMT2D/ALL1 Polyclonal Antibody is a Rabbit antibody targeting KMT2D/ALL1. Anti-KMT2D/ALL1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-KMT2D/ALL1 Polyclonal Antibody is a Rabbit antibody targeting KMT2D/ALL1. Anti-KMT2D/ALL1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Sheep) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Expressed in most adult tissues, including a variety of hematoipoietic cells, with the exception of the liver. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome. [provided by RefSeq, Oct 2010] |
| Immunogen | KLH conjugated synthetic peptide: human KMT2D/ALL1 |
| Antigen Species | Human |
| Gene Name | KMT2D |
| Gene ID | |
| Protein Name | Histone-lysine N-methyltransferase 2D |
| Uniprot ID | |
| Function | Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription. Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development. Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation. |
| Molecular Weight | Theoretical: 593 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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