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Anti-NIMP/RTN4IP1 Polyclonal Antibody
😃Good
Catalog No. TMAB-09479
Anti-NIMP/RTN4IP1 Polyclonal Antibody is a Rabbit antibody targeting NIMP/RTN4IP1. Anti-NIMP/RTN4IP1 Polyclonal Antibody can be used in WB.
Anti-NIMP/RTN4IP1 Polyclonal Antibody
Anti-NIMP/RTN4IP1 Polyclonal Antibody
😃Good
Catalog No. TMAB-09479
Anti-NIMP/RTN4IP1 Polyclonal Antibody is a Rabbit antibody targeting NIMP/RTN4IP1. Anti-NIMP/RTN4IP1 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-NIMP/RTN4IP1 Polyclonal Antibody is a Rabbit antibody targeting NIMP/RTN4IP1. Anti-NIMP/RTN4IP1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Pig,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion. |
| Tissue Specificity | Widely expressed in mitochondria-enriched tissues. Found in heart, muscle, kidney, liver, brain and placenta. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Appears to be a potent inhibitor of regeneration following spinal cord injury.Nogo is an oligodendrocyte-specific member of the Reticulon family and is a component of CNS white matter that inhibits axon outgrowth, induces collapse of growth cones of chick dorsal root ganglion cells, and inhibits the spreading of 3T3 fibroblasts. Nogo is expressed by oligodendrocytes but not by Schwann cells, and associates primarily with the endoplasmic reticulum. Nogo exists in three different splice forms, Nogo-A, -B and -C. NIMP (NOGO-interacting mitochondrial protein), also known as RTN4IP1 (Reticulon-4-interacting protein 1), is a 396 amino acid mitochondrial protein that contains a C-terminal oxidoreductaselike domain and numerous sites for phosphorylation. NIMP is expressed in mitochondrial-rich tissue such as kidney, heart, skeletal muscle and specific regions within the nervous system. Through interaction with Nogo, it is likely that NIMP plays a role in Nogo-induced inhibition of neurite growth. There are three isoforms of NIMP that are produced as a result of alternative splicing events. |
| Immunogen | KLH conjugated synthetic peptide: human NIMP/RTN4IP1 |
| Antigen Species | Human |
| Gene Name | RTN4IP1 |
| Gene ID | |
| Protein Name | Reticulon-4-interacting protein 1, mitochondrial |
| Uniprot ID | |
| Function | Appears to be a potent inhibitor of regeneration following spinal cord injury. |
| Molecular Weight | Theoretical: 39 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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