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Anti-Phospho-c-Fos (Thr232) Polyclonal Antibody

Catalog No. TMAB-10493 Copy Product Info
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Anti-Phospho-c-Fos (Thr232) Polyclonal Antibody is a Rabbit antibody targeting Phospho-c-Fos (Thr232). Anti-Phospho-c-Fos (Thr232) Polyclonal Antibody can be used in WB.

Anti-Phospho-c-Fos (Thr232) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-10493

Anti-Phospho-c-Fos (Thr232) Polyclonal Antibody is a Rabbit antibody targeting Phospho-c-Fos (Thr232). Anti-Phospho-c-Fos (Thr232) Polyclonal Antibody can be used in WB.

Anti-Phospho-c-Fos
(Thr232) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-c-Fos (Thr232) Polyclonal Antibody is a Rabbit antibody targeting Phospho-c-Fos (Thr232). Anti-Phospho-c-Fos (Thr232) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse
Verified Activity
Sample: Cerebrum (Mouse) Lysate at 40 μg
Primary: Anti-Phospho-c-Fos (Thr232) (TMAB-10493) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 41 kD
Observed band size: 48 kD
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008].
Antigen Details
Immunogen
KLH conjugated Synthesised phosphopeptide: mouse c-Fos around the phosphorylation site of Thr232
Antigen Species
Mouse
Gene Name
FOS
Gene ID
14281
Protein Name
Proto-oncogene c-Fos
Uniprot ID
P01101
Function
Nuclear phosphoprotein which forms a tight butnon-covalently linked complex with the JUN/AP-1 transcriptionfactor. In the heterodimer, FOS and JUN/AP-1 basic regions eachseems to interact with symmetrical DNA half sites. On TGF-betaactivation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at theAP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Hasa critical function in regulating the Has a critical function inregulating the development of cells destined to form and maintainthe skeleton. It is thought to have an important role in signaltransduction, cell proliferation and differentiation.
Chemical Properties
Molecular WeightTheoretical: 41 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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